The GLP-1 User’s Guide to Panera Bread

By Sydney Duong, RD · 2026-02-27

Master your GLP-1 nutrition goals at Panera Bread. Learn how to use the "You Pick Two" menu to maximize protein and fiber while managing smaller appetites.

Panera Bread is a standout option for those on GLP-1 medications like Wegovy or Zepbound because of its emphasis on whole-food ingredients and highly customizable menu. The "You Pick Two" menu allows you to enjoy half a sandwich or salad now and save the other half for a second "mini-meal" 2–3 hours later to accommodate a lesser appetite. This approach also allows you to pair a high-protein item with a high-fiber item to hit multiple nutrient goals in one order. Here are some of our top picks from Panera’s menu for GLP-1 success. 

Breakfast Options

1. Garden Avocado & Egg White Sandwich

Best for: Overall balanced macronutrient profile. 

• The Order: Garden Avocado & Egg White Sandwich on a Multigrain Bagel Flat.

• Nutrition: 340 Calories | 19g Protein | 14g Fat | 36g Carbs | 5g Fiber.

• Pro Tip: Requesting the Multigrain Bagel Flat provides a manageable extra 3g of fiber while keeping the portion size lighter than a standard bagel.

2. Steel Cut Oatmeal with Strawberries & Pecans

Best for: Maximum fiber to support digestion.

• The Order: Steel Cut Oatmeal with Strawberries & Pecans.

• Nutrition: 330 Calories | 8g Protein | 13g Fat | 51g Carbs | 9g Fiber.

• Pro Tip: While the 9g of fiber is excellent for digestive regularity, the protein is low. Pair this with two hard-boiled eggs (available as a side) to add 13g of protein for a more balanced meal.

Lunch & Dinner Recommendations

1. You-Pick-Two Half Green Goddess Chicken Cobb Salad + Cup of Hearty Fireside Chili

Best for: A powerhouse of protein and phytonutrients.

• The Order: Half Green Goddess Chicken Cobb Salad and a Cup of Hearty Turkey Chili.

• Nutrition: 520 Calories | 33g Protein | 24g Fat | 43g Carbs | 10 Fiber

• Why it works: This meal is rich in phytonutrients. These are natural plant compounds that provide antioxidant and anti-inflammatory benefits. The Green Goddess dressing, avocado, tomatoes, and chili peppers offer a spectrum of these nutrients to support overall health during weight loss.

2. Mediterranean Chicken Greens with Grains

Best for: Sustained energy and blood sugar balance.

• The Order: Mediterranean Chicken Greens with Grains Salad (No Dressing)

• Nutrition: 440 Calories | 35g Protein | 16g Fat | 43g Carbs | 7 Fiber

• Dietitian Tip: Because this portion might be too much for a single sitting, order the half-size or plan to save half for later. Request the Greek dressing on the side to control the fat content, as the feta and hummus already provide plenty of healthy fats.

3. Half Tuna Salad Sandwich

Best for: Easy-to-digest protein.

• The Order: Half Tuna Salad Sandwich

• Nutrition (Half): 270 Calories | 12g Protein | 14g Fat | 25g Carbs | 2 Fiber

• Dietitian Tip: Tuna is generally considered an easy to digest protein compared to other meat due to its low fat content and lesser amount of chewy connective tissue. Tuna salad can be high in fat due to the mayo. To keep it light, we suggest you request no extra mayo and keep your portion to a half sandwich.

The Bottom Line

By utilizing the above strategies, you can easily navigate the Panera menu to find meals that respect your appetite while hitting your nutrient goals. Focusing on high-protein, fiber-rich pairings ensures you are fueling your body effectively and supporting your GLP-1 success.