What is pancreatitis?

Pancreatitis is inflammation of the pancreas; it's a rare but serious GLP-1 side effect — severe persistent abdominal pain (often radiating to the back) warrants stopping the drug and calling your provider.

Pancreatitis is inflammation of the pancreas; it's a rare but serious GLP-1 side effect — severe persistent abdominal pain (often radiating to the back) warrants stopping the drug and calling your provider. Real-world rates of pancreatitis on GLP-1s are very low, but the risk is higher than baseline. People with a personal history of pancreatitis or gallstone disease should discuss the risk profile with their prescriber. Warning signs: severe persistent upper-abdominal pain (sometimes radiating to the back), often with nausea or vomiting. This is not typical titration nausea — it's intense and doesn't resolve with eating or rest. If pancreatitis is confirmed, GLP-1s are generally stopped permanently. Routine dose-titration GI symptoms are not pancreatitis.

Related pages

• Ozempic side effects in week 1
• GLP-1 glossary

Get the GLPeak app

Download GLPeak on the App Store · Get GLPeak on Google Play